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Q10.4(c):
Explain why (c) The size of the needle of a syringe controls flow rate better than the thumb pressure exerted by a doctor while administering an injection

Solution :

Theoretical Foundation: Poiseuille’s Law

To analyze the flow rate ($Q$) of an incompressible, viscous fluid through a cylindrical needle, we employ Poiseuille’s Law. The equation is defined as:

$Q = \frac{\pi \Delta P r^4}{8 \eta L}$

Where:

  • $Q$ = Volumetric flow rate ($m^3/s$)
  • $\Delta P$ = Pressure difference applied by the doctor ($Pa$)
  • $r$ = Internal radius of the needle ($m$)
  • $\eta$ = Coefficient of viscosity of the fluid ($Pa \cdot s$)
  • $L$ = Length of the needle ($m$)

Step 1: Sensitivity Analysis of Variables

We examine the mathematical dependence of the flow rate $Q$ on the independent variables: pressure ($\Delta P$) and radius ($r$).

  1. Dependence on Pressure ($\Delta P$): The relationship is linear, represented as $Q \propto \Delta P$. A change in thumb pressure results in a directly proportional change in flow rate.
  2. Dependence on Radius ($r$): The relationship is quartic (fourth-power), represented as $Q \propto r^4$. This implies that even a marginal variation in the internal radius of the needle exerts a massive influence on the flow rate.

Step 2: Comparative Magnitude of Influence

Let us consider a scenario where we evaluate the impact of a 10% change in both variables:

  • Effect of Pressure: A 10% increase in $\Delta P$ results in a 10% increase in $Q$.
  • Effect of Radius: A 10% increase in $r$ (i.e., new radius $r' = 1.1r$) results in:
    $(1.1)^4 \approx 1.4641$
    This represents a 46.41% increase in flow rate.

Step 3: Clinical and Engineering Implications

The needle radius serves as a "choke point" or a primary resistance component within the fluid system [Per the principle of Fluid Resistance].

Needle Geometry (Radius r) Flow Rate Q ∝ r⁴ (Dominant Factor) ΔP (Thumb Pressure)

Conclusion on Control Mechanisms

The human hand lacks the precision to maintain a perfectly constant $\Delta P$ during an injection. Because $Q$ is extremely sensitive to $r$, the physical dimensions of the needle define the baseline delivery rate. The needle size acts as a mechanical regulator that dampens the fluctuations caused by the human operator, ensuring a controlled, predictable delivery of medication that would otherwise be erratic if dependent solely on manual force.

Final Solution: The flow rate is governed by $Q \propto r^4$, making it mathematically hypersensitive to the needle's internal radius compared to the linear relationship $Q \propto \Delta P$ with thumb pressure. Therefore, needle selection is the primary determinant for flow regulation.


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