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Q3(b):
How does the transmission of each of the following diseases take place? (b) Malaria

Solution :

1. Pathogen and Vector Identification

Malaria is a protozoan infection caused by species of the genus Plasmodium (specifically P. falciparum, P. vivax, P. malariae, and P. ovale). The transmission of this pathogen is strictly biological, requiring an intermediate host and a definitive host [Per biological classification of parasitic life cycles].

  • Definitive Host: Female Anopheles mosquito (where sexual reproduction occurs).
  • Intermediate Host: Human (where asexual multiplication occurs).

2. The Mechanism of Transmission

The transmission process follows a precise sequential biological protocol:

  1. Inoculation: When an infected female Anopheles mosquito bites a healthy human to take a blood meal, it injects the sporozoites (the infectious stage of Plasmodium) from its salivary glands into the human bloodstream.
  2. Circulatory Phase: The sporozoites travel through the blood to reach the liver, initiating the exo-erythrocytic cycle [Biological life cycle of Plasmodium].
  3. Acquisition: When a mosquito bites an already infected individual, it ingests the gametocytes (male and female) present in the human blood.
  4. Development in Vector: Fertilization and development take place in the mosquito's gut, resulting in the formation of sporozoites which migrate to the salivary glands, ready for the next human host.

3. Visual Representation of Transmission Cycle

Injection of Sporozoites Ingestion of Gametocytes Mosquito Human Host

4. Epidemiological Summary

Component Description
Mode of Transmission Vector-borne transmission via bite of infected female Anopheles mosquito.
Infectious Agent Plasmodium (Protozoa).
Infectious Form Sporozoites.

Final Solution: Malaria is transmitted to humans exclusively through the bite of an infected female Anopheles mosquito, which acts as the biological vector by injecting sporozoites into the human bloodstream during a blood meal.


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