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Q6(i):
Name the stage of cell cycle at which one of the following events occur: (i) Chromosomes are moved to spindle equator.

Solution :

Step 1: Identifying the Biological Context

The movement of chromosomes to the spindle equator is a critical regulatory event during the M-phase (Mitosis) of the eukaryotic cell cycle. This phase is characterized by the physical segregation of replicated sister chromatids into two daughter nuclei. [Per the Cell Theory and the mechanics of Mitosis].

Step 2: Analysis of the Metaphase Stage

During the process of nuclear division, the transition from prophase to metaphase involves the attachment of kinetochores of sister chromatids to spindle fibers. The specific event where chromosomes align at the equatorial plane—a structure termed the metaphase plate—defines the stage known as Metaphase.

Chromosome Metaphase Plate

Step 3: Theoretical Justification

  • Kinetochore Attachment: The spindle fibers from opposite poles of the cell attach to the kinetochores of each sister chromatid. [Mechanism of Spindle Assembly Checkpoint].
  • Forces of Alignment: The chromosomes are moved via the polymerization and depolymerization of microtubules, resulting in a tension equilibrium at the center of the cell.
  • Biological Significance: Alignment at the equator ensures that each daughter cell receives an identical set of chromosomes during the subsequent Anaphase. [Per the Law of Segregation and Mitotic Fidelity].

Step 4: Summary Table of Chromosomal Dynamics

Phase Primary Event
Prophase Condensation of chromatin into chromosomes.
Metaphase Chromosomes align at the equator.
Anaphase Sister chromatids split and move to opposite poles.

Final Solution: The stage of the cell cycle at which chromosomes are moved to the spindle equator is Metaphase.


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