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Q15:
Who had proposed the chromosomal theory of the inheritance?
Solution :
Historical Context & Theoretical Foundation
The Chromosomal Theory of Inheritance serves as a fundamental pillar of modern genetics, establishing that genes are located at specific loci on chromosomes and that the behavior of chromosomes during meiosis accounts for the principles of Mendelian inheritance [Per the Sutton-Boveri hypothesis].
Step 1: Identifying the Proponents
The theory was proposed independently by two American biologists in the year 1902:
- Walter Sutton: A graduate student who observed the behavior of chromosomes during meiosis in grasshopper cells.
- Theodor Boveri: A German biologist who conducted experiments on sea urchin eggs, demonstrating that individual chromosomes are required for proper embryonic development.
Step 2: Analytical Comparison of Mendelian Factors and Chromosomes
Sutton and Boveri identified striking parallels between the segregation of Mendel's "factors" (genes) and the behavior of chromosomes during meiosis. These are summarized in the following table:
| Feature | Mendelian Factors (Genes) | Chromosomes |
|---|---|---|
| Occurrence | In pairs in diploid organisms | In pairs in diploid organisms |
| Segregation | Segregate at gamete formation | Segregate at meiosis (Anaphase I) |
| Independence | Independent assortment | Independent assortment |
Step 3: Visual Representation of Chromosomal Segregation
The following diagram illustrates the movement of homologous chromosomes during Meiosis I, confirming that the physical separation of chromosomes provides the mechanism for the segregation of alleles [By the Law of Segregation].
Synthesized Conclusion
By correlating the movement of chromosomes during meiosis with the patterns of inheritance observed by Gregor Mendel, Sutton and Boveri successfully bridged the gap between cytology and genetics, providing the physical basis for heredity.
Final Solution: The Chromosomal Theory of Inheritance was proposed by Walter Sutton and Theodor Boveri in 1902.
More Questions from Class 12 Biology Principles of Inheritance and Variation EXERCISES
- Q1: Mention the advantages of selecting pea plant for experiment by Mendel.
- Q1: Mention the advantages of selecting pea plant for experiment by Mendel.
- Q2(a): Differentiate between the following – (a) Dominance and Recessive
- Q2(a): Differentiate between the following – (a) Dominance and Recessive
- Q2(b): Differentiate between the following – (b) Homozygous and Heterozygous
- Q2(b): Differentiate between the following – (b) Homozygous and Heterozygous
- Q2(c): Differentiate between the following – (c) Monohybrid and Dihybrid.
- Q2(c): Differentiate between the following – (c) Monohybrid and Dihybrid.
- Q3: A diploid organism is heterozygous for 4 loci, how many types of gametes can be produced?
- Q3: A diploid organism is heterozygous for 4 loci, how many types of gametes can be produced?
- Q4: Explain the Law of Dominance using a monohybrid cross.
- Q4: Explain the Law of Dominance using a monohybrid cross.
- Q5: Define and design a test-cross.
- Q5: Define and design a test-cross.
- Q6: Using a Punnett Square, workout the distribution of phenotypic features in the first filial generation after a cross between a homozygous female and a heterozygous male for a single locus.
- Q6: Using a Punnett Square, workout the distribution of phenotypic features in the first filial generation after a cross between a homozygous female and a heterozygous male for a single locus.
- Q7(a): When a cross in made between tall plant with yellow seeds (\(TtYy\)) and tall plant with green seed (\(Ttyy\)), what proportions of phenotype in the offspring could be expected to be (a) tall and green.
- Q7(a): When a cross in made between tall plant with yellow seeds ((TtYy)) and tall plant with green seed ((Ttyy)), what proportions of phenotype in the offspring could be expected to be (a) tall and green.
- Q7(b): When a cross in made between tall plant with yellow seeds (\(TtYy\)) and tall plant with green seed (\(Ttyy\)), what proportions of phenotype in the offspring could be expected to be (b) dwarf and green.
- Q7(b): When a cross in made between tall plant with yellow seeds ((TtYy)) and tall plant with green seed ((Ttyy)), what proportions of phenotype in the offspring could be expected to be (b) dwarf and green.
- Q8: Two heterozygous parents are crossed. If the two loci are linked what would be the distribution of phenotypic features in \(F_{1}\) generation for a dibybrid cross?
- Q8: Two heterozygous parents are crossed. If the two loci are linked what would be the distribution of phenotypic features in (F_{1}) generation for a dibybrid cross?
- Q9: Briefly mention the contribution of T.H. Morgan in genetics.
- Q9: Briefly mention the contribution of T.H. Morgan in genetics.
- Q10: What is pedigree analysis? Suggest how such an analysis, can be useful.
- Q10: What is pedigree analysis? Suggest how such an analysis, can be useful.
- Q11: How is sex determined in human beings?
- Q11: How is sex determined in human beings?
- Q12: A child has blood group O. If the father has blood group A and mother blood group B, work out the genotypes of the parents and the possible genotypes of the other offsprings.
- Q12: A child has blood group O. If the father has blood group A and mother blood group B, work out the genotypes of the parents and the possible genotypes of the other offsprings.
- Q13(a): Explain the following terms with example (a) Co-dominance
- Q13(a): Explain the following terms with example (a) Co-dominance
- Q13(b): Explain the following terms with example (b) Incomplete dominance
- Q13(b): Explain the following terms with example (b) Incomplete dominance
- Q14: What is point mutation? Give one example.
- Q14: What is point mutation? Give one example.
- Q15: Who had proposed the chromosomal theory of the inheritance?
- Q16: Mention any two autosomal genetic disorders with their symptoms.
- Q16: Mention any two autosomal genetic disorders with their symptoms.
CBSE Solutions for Class 12 Biology Principles of Inheritance and Variation
Chapters in CBSE - Class 12 Biology
- Reproduction in Organisms
- Human Reproduction
- Reproductive Health
- Molecular Basis of Inheritance
- Evolution
- Human Health and Disease
- Strategies for Enhancement in Food Production
- Microbes in Human Welfare
- Biotechnology: Principles and Processes
- Biotechnology and Its Applications
- Organisms and Populations
- Ecosystem
- Biodiversity and Conservation
- Environmental Issues
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