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Q13(b):
Explain the following terms with example (b) Incomplete dominance

Solution :

Definition and Theoretical Foundation

Incomplete dominance is a form of intermediate inheritance in which one allele for a specific trait is not completely expressed over its paired allele. This results in a third phenotype in which the expressed physical trait is a combination of the phenotypes of both alleles. [Per Mendelian Genetics, this violates the Law of Dominance, which states that the dominant allele should completely mask the recessive allele in the heterozygous condition.]

Mechanism of Action

In incomplete dominance, the phenotypic ratio in the $F_2$ generation deviates from the classic Mendelian ratio of $3:1$. Instead, it follows a genotypic and phenotypic ratio of $1:2:1$ ($1$ homozygous dominant : $2$ heterozygous : $1$ homozygous recessive).

Biological Example: Antirrhinum majus (Snapdragon)

In Antirrhinum majus, flower color is determined by a pair of alleles: $R$ (Red) and $r$ (White). When a pure-breeding red-flowered plant ($RR$) is crossed with a pure-breeding white-flowered plant ($rr$), the $F_1$ generation produces pink flowers ($Rr$).

Generation Parental/Offspring Genotype Phenotype
Parental ($P$) $RR \times rr$ Red $\times$ White
$F_1$ Generation $Rr$ Pink (Intermediate)
$F_2$ Generation $1RR : 2Rr : 1rr$ $1$ Red : $2$ Pink : $1$ White

Visual Representation of the Cross

RR (Red) rr (White) F1: Rr (Pink) Phenotype: Intermediate

Genetic Rationale

  • Genotype $RR$: The dominant allele produces functional enzymes necessary for full red pigment synthesis.
  • Genotype $rr$: The recessive allele produces a non-functional enzyme, resulting in no pigment (White).
  • Genotype $Rr$: A single copy of the dominant allele is insufficient to produce the full intensity of the red pigment, leading to a diluted, intermediate pink color. This is an example of dosage-dependent gene expression.

Final Solution: Incomplete dominance is the phenomenon where the dominant allele does not completely mask the recessive allele, resulting in an intermediate phenotype. In the snapdragon (Antirrhinum majus), a cross between red-flowered ($RR$) and white-flowered ($rr$) plants results in pink ($Rr$) $F_1$ offspring, demonstrating this inheritance pattern.


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