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The suprachiasmatic nucleus (SCN) of the hypothalamus acts as the master clock or central pacemaker of the circadian rhythm in humans. The SCN is a small group of cells located above the optic chiasm and receives direct input from the retina, allowing it to synchronize with the light-dark cycle of the external environment. The SCN generates endogenous rhythms with a period close to 24 hours, which serve to regulate various physiological and behavioral processes, including sleep-wake cycles, hormone secretion, body temperature, and metabolism. The SCN coordinates the timing of these circadian rhythms throughout the body, helping to maintain internal synchrony and adapt to environmental changes.
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