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CBSE - Class 12 Biology Molecular Basis of Inheritance Worksheet

1.
How did Hershey and Chase differentiate between DNA and protein in their experiment while proving that DNA is the genetic material?
2.
List two essential roles of ribosome during translation.
3.
Briefly describe the following:
(a) Transcription
4.
What is DNA fingerprinting? Mention its application.
5.
Briefly describe the following:
(c) Translation
6.
Briefly describe the following:
(b) Polymorphism
7.
If the sequence of one strand of DNA is written as follows:
5' -ATGCATGCATGCATGCATGCATGCATGC-3'
Write down the sequence of complementary strand in 5'\(\rightarrow\)3' direction.
8.
Explain (in one or two lines) the function of the followings:
(b) tRNA
9.
Explain (in one or two lines) the function of the followings:
(a) Promoter
10.
Explain (in one or two lines) the function of the followings:
(c) Exons
11.
If a double stranded DNA has 20 per cent of cytosine, calculate the per cent of adenine in the DNA.
12.
Why is the Human Genome project called a mega project?
13.
Group the following as nitrogenous bases and nucleosides:
Adenine, Cytidine, Thymine, Guanosine, Uracil and Cytosine.
14.
Differentiate between the followings:
(c) Template strand and Coding strand
15.
If the sequence of the coding strand in a transcription unit is written as follows:
5' -ATGCATGCATGCATGCATGCATGCATGC-3'
Write down the sequence of mRNA.
16.
Depending upon the chemical nature of the template (DNA or RNA) and the nature of nucleic acids synthesised from it (DNA or RNA), list the types of nucleic acid polymerases.
17.
In the medium where E. coli was growing, lactose was added, which induced the lac operon. Then, why does lac operon shut down some time after addition of lactose in the medium?
18.
Which property of DNA double helix led Watson and Crick to hypothesise semi-conservative mode of DNA replication? Explain.
19.
Differentiate between the followings:
(b) mRNA and tRNA
20.
Briefly describe the following:
(d) Bioinformatics

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